Synthesis and Biological Evaluation of Novel Quinoline Derivatives as Antibacterial and Antifungal Agents
نویسندگان
چکیده مقاله:
Vilsmeier Several diamide derivatives containing 2-chloroquinoline scaffolds were synthesized via Ugi reaction of 2-chloroquinoline-3-carboxaldehydes, amines, carboxylic acids and isocyanides. The diversity of these quinolinyl Ugi-adducts was increased by using 2-chloroquinoline-3-carboxylic acids as a source of acid. Among them, compounds 2d, 2n, 2p, 4a, 4c and 4e displayed moderate to good antibacterial and antifungal activity.
منابع مشابه
synthesis and biological evaluation of novel quinoline derivatives as antibacterial and antifungal agents
vilsmeier several diamide derivatives containing 2-chloroquinoline scaffolds were synthesized via ugi reaction of 2-chloroquinoline-3-carboxaldehydes, amines, carboxylic acids and isocyanides. the diversity of these quinolinyl ugi-adducts was increased by using 2-chloroquinoline-3-carboxylic acids as a source of acid. among them, compounds 2d, 2n, 2p, 4a, 4c and 4e displayed moderate to good an...
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عنوان ژورنال
دوره 2 شماره 2
صفحات 113- 119
تاریخ انتشار 2016-09-01
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